https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Optimal CT perfusion thresholds for core and penumbra in acute posterior circulation infarction https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:53333 1 s and MTT>145%. Delay time (DT) best estimated the infarct core (AUC = 0.74). The optimal core threshold was a DT >1.5 s. The voxel-based analyses indicated CTP was most accurate in the calcarine (Penumbra-AUC = 0.75, Core-AUC = 0.79) and cerebellar regions (Penumbra-AUC = 0.65, Core-AUC = 0.79). For the volume-based analyses, MTT >160% demonstrated best correlation and smallest mean-volume difference between the penumbral estimate and follow-up MRI (R2 = 0.71). MTT >170% resulted in the smallest mean-volume difference between the core estimate and follow-up MRI, but with poor correlation (R2 = 0.11). Conclusion: CTP has promising diagnostic utility in POCI. Accuracy of CTP varies by brain region. Optimal thresholds to define penumbra were DT >1 s and MTT >145%. The optimal threshold for core was a DT >1.5 s. However, CTP core volume estimates should be interpreted with caution.]]> Wed 28 Feb 2024 16:20:57 AEDT ]]> Impaired cerebrovascular responsiveness and cognitive performance in adults with type 2 diabetes https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:31031 Wed 19 Jan 2022 15:17:45 AEDT ]]> Effects of long-chain omega-3 polyunsaturated fatty acids on endothelial vasodilator function and cognition-are they interrelated? https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:30472 Wed 11 Apr 2018 12:58:04 AEST ]]> Acute resveratrol consumption improves neurovascular coupling capacity in adults with type 2 diabetes mellitus https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:25049 Thu 28 Oct 2021 13:05:05 AEDT ]]> Regional changes with global brain hypometabolism indicates a physiological triage phenomenon and can explain shared pathophysiological events in Alzheimer's & small vessel diseases and delirium. https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:48100 Fri 24 Feb 2023 15:31:10 AEDT ]]>